Ciprolet (Ciprofloxacin) 500 mg tablets 10
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Active substance: ciprofloxacin hydrochloride 582.211 mg, which corresponds to the content of ciprofloxacin 50 mg.
Excipients: corn starch - 27.789 mg, microcrystalline cellulose - 5 mg, croscarmellose sodium - 20 mg, silicon dioxide colloidal - 5 mg, talc - 6 mg, magnesium stearate - 4.5 mg.
Shell composition: hypromellose (6 cps) - 5 mg, sorbic acid - 0.072 mg, titanium dioxide - 1.784 mg, talc - 1.784 mg, macrogol 6000 - 1.216 mg, polysorbate 80 - 0.072 mg, dimethicone - 0.072 mg.
Antibacterial drug of a wide spectrum of action from the group of fluoroquinolones. It acts bactericidal. The drug inhibits the enzyme DNA-gyrase of bacteria, as a result of which DNA replication and synthesis of bacterial cellular proteins are disrupted.
Ciprofloxacin acts both on multiplying microorganisms and on those in the resting phase.
Indications for use
Infectious and inflammatory diseases caused by microorganisms sensitive to ciprofloxacin, including:
- respiratory tract infections;
- infections of ENT organs;
- infections of the kidneys and urinary tract;
- genital infections;
- infections of the gastrointestinal tract (including the mouth, teeth, jaws);
- infections of the gallbladder and biliary tract;
- infections of the skin, mucous membranes and soft tissues;
- infections of the musculoskeletal system;
Prevention and treatment of infections in patients with reduced immunity (with immunosuppressant therapy).
- pseudomembranous colitis;
- lactation (breastfeeding);
- children and adolescents up to 18 years;
- hypersensitivity to ciprofloxacin or other drugs from the group of fluoroquinolones.
With caution, the drug should be prescribed for severe atherosclerosis of the cerebral vessels, cerebral circulation disorders, mental illness, convulsive syndrome, epilepsy, severe renal and / or liver failure, as well as elderly patients.
Use in pregnancy and lactationThe drug is contraindicated for use during pregnancy and lactation.
Patients with epilepsy, seizures in the anamnesis, vascular diseases and organic brain lesions in connection with the threat of adverse reactions from the central nervous system Ciprolet ® should be prescribed only for vital indications.
If severe and prolonged diarrhea occurs during or after treatment with Ciprolet, the diagnosis of pseudomembranous colitis should be excluded, which requires immediate discontinuation of the drug and the appointment of appropriate treatment.
If tendon pain occurs or when the first signs of tendovaginitis appear, treatment should be discontinued due to the fact that isolated cases of inflammation and even tendon rupture during treatment with fluoroquinolones are described.
During the period of treatment with Ciprolet, it is necessary to provide a sufficient amount of fluid while observing normal diuresis.
During the period of treatment with Ciprolet, contact with direct sunlight should be avoided.
Influence on the ability to drive vehicles and control mechanisms
Patients taking Ciprolet ® , caution should be exercised when driving a car and engaging in other potentially dangerous activities that require increased attention and speed of psychomotor reactions (especially with the simultaneous use of alcohol).
Dosage and Administration
The dose of Ciprolet depends on the severity of the disease, the type of infection, the state of the body, age, body weight and kidney function.
In uncomplicated diseases of the kidneys and urinary tract, 250 mg 2 times / day are prescribed, and in severe cases - 500 mg 2 times / day.
In diseases of the lower respiratory tract of moderate severity - 250 mg 2 times / day, and in more severe cases - 500 mg 2 times / day.
For the treatment of gonorrhea, a single dose of Ciprolet® is recommended at a dose of 250-500 mg.
In gynecological diseases, enteritis and colitis with severe course and high fever, prostatitis, osteomyelitis is prescribed at 500 mg 2 times / day (for the treatment of ordinary diarrhea can be used at a dose of 250 mg 2 times / day).
Tablets should be taken on an empty stomach, washed down with a sufficient amount of liquid.
The duration of treatment depends on the severity of the disease, but treatment should always continue for at least another 2 days after the symptoms of the disease disappear. Usually the duration of treatment is 7-10 days.
Treatment: it is necessary to carefully monitor the patient's condition, do a gastric lavage, carry out the usual emergency measures, ensure a sufficient supply of fluid.
With the help of hemo- or peritoneal dialysis, only a small (less than 10%) amount of the drug can be removed. The specific antidote is unknown.
From the digestive system: nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, cholestatic jaundice (especially in patients with previous liver diseases), hepatitis, hepatonecrosis, increased activity of hepatic transaminases and ALP.
From the nervous system: dizziness, headache, fatigue, anxiety, tremor, insomnia, nightmares, peripheral paralgesia (anomaly of perception of the feeling of pain), sweating, increased intracranial pressure, anxiety, confusion, depression, hallucinations, as well as other manifestations of psychotic reactions (occasionally progressing to conditions in which the patient can harm himself), migraine, fainting, thrombosis of the cerebral arteries.
From the senses: impaired taste and smell, visual impairment (diplopia, change in color perception), tinnitus, hearing loss.
From the cardiovascular system: tachycardia, heart rhythm disturbances, decreased blood pressure, hot flashes to the skin of the face.
From the hematopoietic system: leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia.
On the part of laboratory indicators: hypoprothrombinemia, hypercreatininemia, hyperbilirubinemia, hyperglycemia.
From the urinary system: hematuria, crystalluria (primarily with alkaline urine and low diuresis), glomerulonephritis, dysuria, polyuria, urinary retention, albuminuria, urethral bleeding, hematuria, decreased nitrogen-excreting function of the kidneys, interstitial nephritis.
Allergic reactions: skin itching, urticaria, blisters accompanied by bleeding and small nodules forming scabs, drug fever, point hemorrhages (petechiae), swelling of the face or larynx, shortness of breath, eosinophilia, increased photosensitivity, vasculitis, erythema nodosum, exudative erythema multiforme, Stevens-Johnson syndrome (malignant exudative erythema), toxic epidermal necrolysis (Lyell's syndrome).
From the musculoskeletal system: arthralgia, arthritis, tendovaginitis, tendon ruptures, myalgia.
Other: general weakness, superinfections (candidiasis, pseudomembranous colitis).
The drug should be stored in a dry, protected from light, out of the reach of children at temperatures up to 25 ° C.
- Dr. Reddy`s laboratories
- Dosage form
- 500 mg
- Number of tablets
- INN Russian
- Russian title