Dekaris (Levamisole) 50mg tablets 2
Women's clothing size
With your arms relaxed at your sides, measure around the fullest part of your chest.
Measure around the narrowest part of your natural waist, generally around the belly button. To ensure a comfortable fit, keep one finger between the measuring tape and your body.
1 tablet contains:
Active substance: levamisole hydrochloride - 59 mg, which corresponds to the content of levamisole - 50 mg;
Excipients: corn starch, sodium saccharinate, talc, povidone, apricot flavor, magnesium stearate, sunset yellow dye (E110).
Levamisole is an anthelmintic drug. Acting on ganglion-like formations of nematodes, Dekaris causes a depolarizing neuromuscular paralysis of the membrane of the muscles of helminths, blocks succinate dehydrogenase, inhibits fumarate dehydrogenase, disrupting the course of bioenergetic processes of helminths. Thus, paralyzed nematodes are removed from the body by normal intestinal motility within 24 hours after taking the drug.
Levamisole when taken orally at a dose of 50 mg is rapidly absorbed from the gastrointestinal tract. The maximum concentration in the blood plasma is determined on average 1.5-2 hours after taking the drug. Levamisole undergoes intensive metabolism in the liver, its main metabolites are p-hydroxy-levamisole and its glucuronide.
T1 / 2 from the body is 3-6 h. Unchanged, the kidneys excrete less than 5%, through the intestines less than 0.2% of the administered dose.
Indications for use
Infections with helminths Ascaris lumbrocoides, Necator and Americanus Ancylostoma duodenale.
- Agranulocytosis caused by drugs (in the anamnesis).
- Children's age up to 3 years.
- Breastfeeding period.
- Tablets of 150 mg are not prescribed to children.
With caution: patients with renal and / or hepatic insufficiency, with inhibition of bone marrow hematopoiesis.
Dosage and Administration
- Adults: 1 tablet of 150 mg is prescribed once.
- Children aged 3 to 6 years (10-20 kg): 25-50 mg (0.5-1 tablet of 50 mg) once.
- Children aged 6 to 10 years (20-30 kg): 50-75 mg (1-1.5 tablets of 50 mg) once.
- Children aged 10 to 14 years (30-40 kg): 75-100 mg (1.5-2 tablets of 50 mg) once.
The drug is advisable to take after meals with a small amount of water, in the evening. There is no need to take laxatives or a special diet. If necessary, the drug can be repeated after 7-14 days.
Headache, insomnia, dizziness, palpitations, convulsions, dyspeptic phenomena (nausea, vomiting, abdominal pain, diarrhea).
There are reports of the development of side effects from the central nervous system (encephalopathy) 2-5 weeks after taking of the drug, as well as allergic reactions (skin rash), convulsions.
In most patients, these phenomena were reversible, and early use of glucocorticosteroid therapy improved the prognosis.
The connection of these symptoms with the reception of Dekaris is not entirely convincing. When using large doses or with prolonged therapy, leukopenia, agranulocytosis, tremor can be observed.
Store at a temperature of 15-30 ° C.
Keep out of reach of children.
- Gedeon Richter Ltd
- Dosage form
- 50 mg
- Number of tablets
- INN Russian
- Russian title