Pyrantel 250mg tablets 3

Country

Poland

INN

Pyrantel

Dosage

250mg

Composition

Active substance: pyrantel pamoate 720 mg, which corresponds to the pyrantel content of 250 mg.

Excipients: gelatin - 5 mg, corn starch - 59 mg, magnesium stearate - 10 mg, sodium carboxymethyl starch - 6 mg, talc purified - 10 mg.

Pharmacological properties

Pyrantel pamoate is a broad-spectrum antihelminthic drug. The mechanism of action is associated with the blocking of neuromuscular conduction in helminths. Active against Enterobius vermicularis, Ascaris Iumbricoidcs, Ancylostoma doudenalc, Necator Ameri-canus, Trichostrongylus oricntalis, Trichostrongylus colubriformis. It acts on both sexually mature and immature individuals of both sexes, does not act on larvae in the migration stage.

Indications for use

Ascariasis, hookworm, necatoriasis and enterobiasis.

Contraindications

• myasthennia (treatment period);
• children's age up to 3 years (solid dosage form);
• hypersensitivity to pyrantel and other components of the drug.

With caution: liver failure.

Use in pregnancy and lactation

During pregnancy, it is used only if the intended benefit to the mother exceeds the risk to the fetus.

When used during lactation, it is recommended to stop breastfeeding.

Use in case of impaired liver function

With caution: liver failure.

Use in children

Contraindicated in children under 3 years of age (solid dosage form). It can be used in children older than 3 years.

Special instructions

After taking pyrantel, a laxative is not prescribed. With enterobiasis, it should be carried out simultaneous treatment of all cohabitants. After the completion of treatment, it is necessary to conduct a control study of feces for the presence of parasite eggs. Careful hygiene is necessary (cleaning of living quarters and cleaning clothes to destroy helminth eggs serves as a prevention of reinfection).

Drug Interactions

Should not be prescribed simultaneously with piperazine (weakening of the action).

With simultaneous use, pyrantel increases the concentration of theophylline in plasma.

Dosage and Administration

The drug is prescribed orally during or after meals and the dosage is set individually depending on the age and body weight of the patient.

Ascariasis and enterobiasis, as well as mixed invasions - once at a dose of 10 mg / kg body weight.

Children 3 to 6 years: 250 mg (1 tab.); children 6 years - 12 years: 500 mg (2 tab.); children over 12 years of age and adults weighing < 75 kg: 750 mg (3 tab.); adults with a body weight of > 75 kg: 1000 mg (4 tab.).

The tablet should be chewed thoroughly.

Hookworm: the drug is prescribed at the rate of - 10 mg / kg body weight per day for 3 days.

Necatorosis: in severe forms, the drug is prescribed at a dose of 20 mg / kg body weight per day for 2 days.

Overdose

Treatment: gastric lavage. There is no specific antidote.

Side effects

From the gastrointestinal tract and liver: decreased appetite, nausea, vomiting, diarrhea, stomach pain are possible; rarely - an increase in the activity of hepatic transaminosis.

From the side of the central nervous system: rarely - headache, dizziness, drowsiness, insomnia, weakness; in some cases - hearing impairment, hallucinations, confusion, paresthesia.

Other: skin rash, urticaria, fever.

Storage conditions

In a dry, dark place at temperature not exceeding 25 ° C. Keep out of reach of children.

Shelf life - 3 years. Do not use an expired drug.

Conditions of release from pharmacies

According to the recipe.