Verapamil-LekT 80 mg tablets 50

Size chart
Women's clothing size
Euro 32/34 36 38 40
USA 0/2 4 6 8
Bust(in) 31-32 33 34 36
Bust(cm) 80.5-82.5 84.5 87 92
Waist(in) 24-25 26 27 29
Waist(cm) 62.5-64.5 66.5 69 74
Hips(in) 34-35 36 37 39
Hips(cm) 87.5-89.5 91.5 94 99
How To Measure Your Bust

With your arms relaxed at your sides, measure around the fullest part of your chest.

How To Measure Your Waist

Measure around the narrowest part of your natural waist, generally around the belly button. To ensure a comfortable fit, keep one finger between the measuring tape and your body.

Volume discounts

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2 35% $12.25
3 41% $21.53
4 53% $37.10
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Active ingredient
80 mg
1 tablet contains:
Active substance: Verapamila hydrochloride - 80 mg. Excipients of the nucleus: Lactose monohydrate (milk sugar) - 30 mg, potato starch - 43.6 mg, calcium stearate - 1.6 mg, talc - 4.8 mg,
Excipients of the shell: polysorbate-80 - 0.76 mg, titanium dioxide - 0.36 mg, methyl cellulose MC-15 - 2.512 mg, beeswax - 0.162 mg, petroleum jelly - 0.2 mg, dye tropeolin-O, or quinoline yellow E-104 - 0.006 mg.
Pharmacological properties

Blocker of "slow" calcium channels (inhibits transmembrane transport of calcium ions to the contractile fibers of smooth muscle cells of the myocardium and coronary vessels). Has antianginal, antiarrhythmic, antihypertensive and hypotensive effect. The antianginal effect is associated both with a direct effect on the myocardium at the level of cellular metabolic processes, and with an indirect effect on the heart muscle by reducing the afterload. Blocking the flow of calcium ions to the contractile fibers of the smooth muscle cells of the coronary arteries, increases myocardial perfusion, even in post-stenotic areas, and eliminates, stops coronary spasm. The hypotensive effect of verapamil is due to a decrease in the total resistance of peripheral vessels without a compensatory increase in heart rate (HEART rate). Verapamil does not affect normal blood pressure (BP). Verapamil has a pronounced antiarrhythmic effect, especially with supraventricular arrhythmia, delays the conduction of the impulse in the atrioventricular (AV) node, as a result of which the sinus rhythm is restored and / or the frequency of ventricular contractions is normalized depending on the type of arrhythmia. Verapamil does not affect or slightly reduces heart rate. The onset of action when taken orally - after 1-2 hours, the maximum effect develops after 30-90 minutes, the duration of action is 8-10 hours.


When taken orally, it is rapidly absorbed in the small intestine, absorption - 90-92%, bioavailability after a single dose - 24-35% due to intensive metabolism during the initial passage through the liver and increases by 1.5-2 times with prolonged use. With prolonged use in increasing doses, bioavailability may increase. The time to reach the maximum concentration (TCmax) when ingested - 1-2 h. Maximum concentration - 80-400 ng / ml. Binding with plasma proteins - 90%. It penetrates the blood-brain barrier, the placental barrier and into breast milk (in low concentrations). It is rapidly metabolized in the liver by N-dealkylation and O-demethylation, with the formation of several metabolites (identified in humans 12). The accumulation of the drug and its metabolites in the body explains the increased action during the course of treatment. The main pharmacologically active metabolite is norvirapamil (20% of the hypotensive activity of verapamil). The isoenzymes CYP3A4, CYP3A5 and CYP3A7 are involved in the metabolism of verapamil. The half-life when ingested is 3-7 hours with a single dose, 4-12 hours - with prolonged use (due to the saturation of the enzyme systems of the liver and an increase in plasma concentrations, the half-life increases by almost 2 times). With liver failure, bioavailability increases and the half-life increases. It is excreted by 70% of the kidneys (3-5% unchanged), 16-25% - through the intestines. It is not excreted in hemodialysis.
Indications for use
- Treatment and prevention of heart rhythm disorders: paroxysmal supraventricular tachycardia; fluttering and flickering of the atria (tachyarrhythmic variant); supraventricular extrasystole;
- Treatment and prevention: chronic stable angina pectoris (angina pectoris); unstable angina; vasospastic angina (Prinzmetal angina, variant angina);
- Treatment of arterial hypertension.
Hypersensitivity to verapamil and other components of the drug; cardiogenic shock; acute myocardial infarction with complications (bradycardia, severe arterial hypotension, left ventricular insufficiency); atrioventricular blockade of II and III degree, with the exception of patients with an artificial pacemaker; syndrome of weakness of the sinus node with the exception of patients with an artificial pacemaker; lactose intolerance, lactase deficiency, glucose-galactose malabsorption; atrial flicker / flutter in the presence of additional pathways (Wolff-Parkinson-White and Laun-Ganong-Levin syndrome); simultaneous use with colchicine; age up to 18 years.
With caution: Atrioventricular blockade of the first degree, chronic heart failure, arterial hypotension, bradycardia, hypertrophic obstructive cardiomyopathy, severe impairment of liver or kidney function, slowing of neuromuscular transmission (myasthenia gravis, Lambert-Eaton syndrome, Duchenne muscular dystrophy), advanced age. Pregnancy and lactation: Data on the clinical use of Verapamil-Ect during pregnancy are insufficient, so the drug should not be used during pregnancy. When using the drug Verapamil-LekT during lactation, it is necessary to stop breastfeeding.
Dosage and Administration
Verapamil-LekT is taken orally during or after meals, washed down with a small amount of water. Tablets are taken whole, without resorption and without chewing, they can not be crushed, divided into parts. The dosage regimen and the duration of treatment are set individually depending on the characteristics the patient's condition, severity, features of the disease and the effectiveness of therapy. The average dose for all recommended indications for use varies from 240 to 480 mg per day. The initial dose is 40-80 mg (it is possible to take verapamil in the dosage form of 40 mg). With prolonged use, do not exceed the maximum daily dose of 480 mg. In the maximum daily dose, the drug should be taken only in a hospital. The duration of therapy is determined by the doctor. In patients with impaired liver function, the excretion of verapamil from the body is slow, so it is advisable to start with a dose of 40 mg 2-3 times a day. The daily dose of the drug should not exceed 120 mg.
Side effects
From the immune system: hypersensitivity reactions. From the central nervous system: headache, dizziness, fainting, anxiety, lethargy, paresthesia, tremor, increased fatigue, asthenia, drowsiness, depression, extrapyramidal disorders (ataxia, "mask-shaped" face, "shuffling" gait, stiffness of the hands or feet, trembling of the hands and fingers, difficulty swallowing). From the side of the organ of hearing: ringing in the ears. From the cardiovascular system: atrioventricular blockade of I, II, III degrees, sinus node arrest, peripheral edema, tachycardia, sinus bradycardia, heart failure, a pronounced decrease in blood pressure, "hot flashes" of blood to the skin of the face, a feeling of palpitations. From the digestive system: nausea, vomiting, constipation, intestinal obstruction, gum hyperplasia, pain or discomfort in the abdomen. From the skin: angioedema, Stevens-Johnson syndrome, maculopapulous rash, urticaria, purpura, skin itching, erythema multiforme, alopecia. From the musculoskeletal system: muscle weakness, myalgia, arthralgia. From the reproductive system and mammary glands: erectile dysfunction, galactorrhea, gynecomastia. On the part of laboratory indicators: increased activity of "hepatic" transaminases, hyperprolactinemia.
Storage conditions
Store at room temperature 15-25 degrees. Keep out of reach of children. Store in a dark place.
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Product Details

Data sheet

Dosage form
80 mg
Number of tablets
INN Russian
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