Arbidol Maximum 200mg capsules 10
Women's clothing size
With your arms relaxed at your sides, measure around the fullest part of your chest.
Measure around the narrowest part of your natural waist, generally around the belly button. To ensure a comfortable fit, keep one finger between the measuring tape and your body.
1 capsule contains umifenovir hydrochloride (in the form of umifenovir hydrochloride monohydrate) - 200 mg.
Excipients: potato starch - 52.67 mg, microcrystalline cellulose - 11.2 mg, silicon dioxide colloidal (aerosil) - 2.8 mg, povidone (collidone 25) - 7.73 mg, calcium stearate - 2.8 mg, croscarmellose sodium - 2.8 mg; weight of the contents of the capsule - 280 mg.
Composition of the capsule shell (body and lid): titanium dioxide (E171) - 1.92 mg, gelatin - 94.08 mg; The total weight of the capsule is 376 mg.
Specifically suppresses in vitro influenza viruses A and B (Influenza virus A, B), including highly pathogenic subtypes A(H1N1)pdm09 and A(H5N1), as well as other viruses - causative agents of ARVI (coronavirus (Coronavirus), associated with severe acute respiratory syndrome (SARS), rhinovirus (Rhinovirus), adenovirus (Adenovirus), respiratory syncytial virus (Pneumovirus) and parainfluenza virus (Paramyxovirus)).
According to the mechanism of antiviral action, it belongs to fusion inhibitors (fusion), interacts with hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes.
It has a moderate immunomodulatory effect, increases the body's resistance to viral infections. It has interferon-inducing activity - in a study on mice, the induction of interferons was noted after 16 hours, and high titers of interferons persisted in the blood until 48 hours after administration.
Stimulates cellular and humoral immune responses: increases the number of lymphocytes in the blood, especially T cells (CD3), increases the number of T-helpers (CD4), without affecting the level of T-suppressors (CD8), normalizes the immunoregulatory index, stimulates the phagocytic function of macrophages and increases the number of natural killers (NK cells).
Therapeutic effectiveness in viral infections is manifested in reducing the duration and severity of the course of the disease and its main symptoms, as well as in reducing the incidence of complications associated with viral infection and exacerbations of chronic bacterial diseases.
Refers to low-toxic drugs (LD 50 >4 g/kg). Does not have any negative effect on the human body when administered orally at recommended doses.
Suction and distribution
Quickly absorbed and distributed to organs and tissues. C max in blood plasma when taken at a dose of 50 mg is achieved after 1.2 hours, at a dose of 100 mg - after 1.5 hours.
Metabolism and excretion
It is metabolized in the liver.
T 1/2 is equal to 17-21 h. About 40% is excreted unchanged, in mainly with bile (38.9%) and in a small amount of kidneys (0.12%). During the first day, 90% of the administered dose is excreted.
Indications for use
- prevention and treatment in adults and children from 12 years of age: influenza A and B, ARVI (including 20 complicated bronchitis, pneumonia), severe acute respiratory syndrome (SARS);
- complex therapy of acute intestinal infections of rotavirus etiology in children older than 12 years;
- complex therapy of chronic bronchitis, pneumonia and recurrent herpes infection;
- prevention of postoperative infectious complications.
- hypersensitivity to the drug;
- children up to 12 years of age.
Dosage and administration
The drug is taken orally, before meals.
A single dose in adults and children over 12 years of age is 200 mg (1 caps.).
For non-specific prevention and treatment of influenza and other ARVI
Non-specific prevention of influenza and other ARVI:
- for nonspecific prevention during the epidemic of influenza and other SARS- 200 mg (1 caps.) 2 times a week for 3 weeks.
- In direct contact with patients with influenza and other SARS, 200 mg (1 caps.) 1 time / day for 10-14 days.
Treatment of influenza and other SARS:
- with an uncomplicated course - 200 mg (1 caps.) 4 times / day (every 6 hours) for 5 days.
- with the development of complications (bronchitis, pneumonia) - 200 mg (1 caps.) 4 times / day (every 6 hours) for 5 days, then a single dose 1 time per week for 4 weeks.
Complex therapy of acute intestinal infections of rotavirus etiology in children older than 12 years
Assign 200 mg (1 caps.) 4 times / day (every 6 hours) for 5 Days.
For non-specific prevention and treatment of severe acute respiratory syndrome (SARS)
For non-specific prevention of SARS (in contact with a patient) - 200 mg (1 caps.) 1 time / day for 12-14 days.
For the treatment of SARS: - 200 mg (1 caps.) 2 times / day for 8-10 days.
In the complex therapy of chronic bronchitis, pneumonia and herpes infection
Assign 200 mg (1 caps.) 4 times / day (every 6 hours) for 5-7 days, then a single dose 2 times a week for 4 weeks.
Prevention of postoperative complications
Assign 200 mg (1 caps.) 2 days before the operation, then on the 2nd and 5th day after the operation.
Rarely: allergic reactions.
The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Conditions vacations from pharmacies
- Dosage form
- 200 mg
- Umifenevir hydrochloride
- Number of tablets
- INN Russian
- Умифеновира гидрохлорид
- Russian title