Lasolvan 30mg tablets 20
Women's clothing size
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Measure around the narrowest part of your natural waist, generally around the belly button. To ensure a comfortable fit, keep one finger between the measuring tape and your body.
1 tablet contains:
Active substances: ambroxol hydrochloride 30 mg;
Excipients: lactose monohydrate - 171 mg, dried corn starch - 36 mg, silicon dioxide colloidal - 1.8 mg, magnesium stearate - 1.2 mg.
Lasolvan - secretomotor, secretolytic, expectorant.
Stimulates serous cells of the glands of the bronchial mucosa, increases the content of mucous secretion and the release of surfactant (surfactant) in the alveoli and bronchi; normalizes the disturbed ratio of serous and mucous components of sputum. By activating hydrolytic enzymes and enhancing the release of lysosomes from Clara cells, it reduces the viscosity of sputum. Increases the motor activity of the cilia of the ciliated epithelium, increases mucociliary transport Sputum.
After oral administration, the action occurs after 30 minutes and lasts for 6-12 hours.
Absorption is high, Cmax is achieved after 2 hours (for tablets, syrup), for oral solution and inhalation - 0.5-3 hours; binding to blood plasma proteins - 80% (for tablets, syrup), for oral solution and inhalation - 90%. It passes through the BBB, placental barrier, is excreted in breast milk. The solution for oral administration and inhalation is quickly distributed in the tissues, the greatest concentration is achieved in the lungs.
It is metabolized in the liver, forms dibromanthranilic acid and glucuronic conjugates. It is excreted by the kidneys - 90% in the form of water-soluble metabolites, 5% - unchanged. About 30% of the dose after oral administration is eliminated through primary metabolism. T1 / 2 - 1.3 hours, for a solution for oral administration and inhalation - 7-12 hours. The half-life increases with severe chronic renal failure, but does not change with impaired liver function.
Indications for use
Acute and chronic respiratory diseases, accompanied by the release of viscous sputum:
- acute and chronic bronchitis;
- bronchial asthma with difficulty in the discharge of sputum;
Hypersensitivity; pregnancy (I trimester).
- II-III trimester of pregnancy;
- lactation period;
- renal and / or hepatic insufficiency.
Dosage and Administration
Inside, after eating, washed down with liquid. Adults - 30 mg (1 tablet) 3 times a day, if necessary, the dose can be increased to 60 mg (2 tablets) 2 times a day.
Allergic reactions: skin rash, urticaria, angioedema, in some cases - allergic contact dermatitis. Cases of acute severe reactions of the anaphylactic type (anaphylactic shock) have rarely been reported.
With prolonged use in high doses - heartburn, gastralgia, nausea, vomiting.
Keep out of reach of children at a temperature not exceeding 30 ° C.
- Boehringer Ingelheim
- Dosage form
- 30 mg
- Number of tablets
- INN Russian
- Russian title