Analgin 500mg tablets 30
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Metamizole sodium - 500 mg.
Analgesic-antipyretic. It is a derivative of pyrazolone. It has an analgesic, antipyretic and anti-inflammatory effect, the mechanism of which is associated with inhibition of the synthesis of prostaglandins.
After oral administration, metamizole sodium is rapidly hydrolyzed in the gastric juice to form the active metabolite 4-methyl-amino-antipyrine, which, after absorption, is metabolized into 4-formyl-amino-antipyrine and other metabolites.
After intravenous administration, metamizole sodium quickly becomes unavailable for determination.
Metabolites of metamizole sodium do not bind to plasma proteins. The largest part of the dose is excreted in the urine in the form of metabolites. Metabolites are excreted in breast milk.
Testimony to use
- Pain syndrome of various genesis (renal and biliary colic, neuralgia, myalgia; with injuries, burns, after operations; headache, toothache, menalgia).
- Fever in infectious and inflammatory diseases.
- Severe impairment of kidney and / or liver function,
- glucose-6-phosphate dehydrogenase deficiency,
- blood diseases,
- hypersensitivity to pyrazolone derivatives.
Dosage and Administration
Inside or rectally adults are prescribed 250-500 mg 2-3 times / day.
The maximum single dose is 1 g, daily dose is 3 g. Single doses for children aged 2-3 years are 50-100 mg; 4-5 years - 100-200 mg; 6-7 years - 200 mg; 8-14 years - 250-300 mg; multiplicity of reception - 2-3 times / day.
Allergic reactions: skin rash, swelling Quincke; rarely - anaphylactic shock.
From the hematopoietic system: rarely, with prolonged use - leukopenia, agranulocytosis.
In a place protected from light, out of the reach of children, at a temperature not exceeding 25 ° C.
- Dosage form
- 500 mg
- Metamizole sodium
- Number of tablets
- INN Russian
- Метамизол натрия
- Russian title