Nazivin 0,05% nasal drops 10ml
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Active substance: oxymetazoline hydrochloride 0.5 mg.
Excipients: citric acid monohydrate - 0.6093 mg, sodium citrate dihydrate - 3.823 mg, glycerol (85%) - 24.348 mg, benzalkonium chloride (50% solution) - 0.100 mg, purified water - 978.600 mg.
Vasoconstrictor preparation for topical use, alpha 2 - Adrenomimetic.
When applied topically to inflamed mucous membranes of the nose, it reduces their swelling and the amount of discharge. Restores nasal breathing. Eliminating the swelling of the mucous membranes, the drug helps to restore aeration of the paranasal sinuses, the cavity of the middle ear and prevents the development of bacterial complications (sinusitis, sinusitis, otitis media).
With local intranasal use in therapeutic concentrations of oxymetazoline does not have a systemic effect, does not irritate the mucous membranes and does not cause hyperemia.
The drug begins to act within a few minutes.
Duration of action up to 12 hours.
Indications for use
- treatment of acute respiratory diseases accompanied by rhinitis;
- allergic rhinitis;
- vasomotor rhinitis;
- restoration of drainage with inflammation of the paranasal sinuses, eustachoitis, otitis mediole;
- elimination of edema before diagnostic manipulations in the nasal passages.
- atrophic rhinitis;
- angle-closure glaucoma;
- children's age up to 6 years (drops and nasal spray 0.05%)
- hypersensitivity to the components of the drug.
Should be adhered to recommended concentrations of the drug, intended for different age categories.
With caution should be prescribed with the simultaneous use of MAO inhibitors and other drugs that contribute to an increase in blood pressure, as well as in the period up to 10 days after the abolition of these drugs; with increased intraocular pressure; during pregnancy and lactation; in severe forms of cardiovascular diseases (arterial hypertension, angina pectoris); with thyrotoxicosis and diabetes mellitus.
Use in pregnancy and lactation
The use of the drug during pregnancy and lactation is possible only after a thorough assessment of the ratio of benefits to the mother and the risk to the fetus or infant. Exceeding the recommended dose is unacceptable.
Long-term use and overdose of the drug should be avoided, especially in children.
Influence on the ability to drive vehicles and control mechanisms.
After prolonged use of drugs containing oxymetazoline, in doses exceeding the recommended, it is impossible to exclude the general effect on the cardiovascular system and the central nervous system; in these cases, the ability to drive a vehicle or equipment may be reduced.
With the simultaneous use of Nazivin with MAO blockers or tricyclic antidepressants, an increase in blood pressure is observed.
Joint administration of other vasoconstrictor drugs increases the risk of side effects.
Dosage and Administration
Intranasal. Nasal drops: adults and children over 6 years of age - 1-2 drops in each nasal passage 2-3 times a day of 0.05% solution; children: infants up to 4 weeks - 1 drop of 0.01% solution 2-3 times a day, from the 5th week of life and up to 1 year - 1-2 drops 2-3 times a day, from 1 year to 6 years - 1-2 drops 2-3 times a day of 0.025% solution.
To ensure Accuracy dosage of Nazivin bottle ® 0.01% of nasal drops have a graduated pipette with marks of the number of drops.
The effectiveness of the following procedure has also been proven: depending on age, 1-2 drops of 0.01% solution are applied to cotton wool and wipe the nasal passages.
Symptoms: with a significant overdose or ingestion, narrowing of the pupils, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, collapse, cardiac depression, arterial hypertension, pulmonary edema, breathing disorders can be observed. In addition, there may be mental disorders, as well as inhibition of the function of the central nervous system, accompanied by drowsiness, a decrease in body temperature, bradycardia, arterial hypotension, respiratory arrest and the possible development of coma.
Treatment: gastric lavage, taking activated charcoal.
Local reactions: sometimes - dryness and burning sensation of the nasal mucosa, sneezing, in rare cases (after the end of nazivin's action) - a feeling of nasal congestion (reactive hyperemia).
From the side of the central nervous system: rarely - anxiety, insomnia, fatigue, headache.
From the digestive system: rarely - nausea.
From the cardiovascular system: with multiple overdose, arterial hypertension, tachycardia are possible.
Long-term continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy and recurrent swelling of the mucous membranes of the nasal cavity (drug rhinitis).
The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Shelf life - 3 years.
- Sofarimex-industry Chemicals and Pharmaceuticals Ltd.
- Dosage form
- Nasal drops
- INN Russian
- Russian title
- 10 ml