Naximin 0.05mg + 5mg nasal spray 15ml
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dexpanthenol + xylometazoline
Active substances: xylometazoline hydrochloride 0.05 mg, dexpanthenol 5 mg.
Excipients: potassium dihydrogen phosphate - 0.9 mg, sodium hydrogen phosphate dihydrate - 0.015 mg, water d / i - up to 100 μl.
Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity, causes narrowing of the blood vessels of the mucous membrane of the nasal cavity, restores the patency of the nasal passages, facilitates nasal breathing. The effect of the drug usually occurs a few minutes after its use and lasts up to 10 hours.
Dexpanthenol is a vitamin of group B - a derivative of pantothenic acid. Dexpanthenol is converted in the body into pantothenic acid, which is an integral part of coenzyme A (Co A) and participates in the processes of acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, corticosteroids, porphyrins; stimulates the regeneration of the skin, mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, metabolic and weak anti-inflammatory effect.
Indications for use
As part of combination therapy to reduce swelling of the nasopharyngeal mucosa:
- acute respiratory diseases with rhinitis;
- acute allergic rhinitis;
- vasomotor rhinitis;
- otitis media.
To facilitate rhinoscopy, restoration of impaired nasal breathing after surgical interventions in the nasal cavity.
- hypersensitivity to the components of the drug;
- arterial hypertension;
- severe atherosclerosis;
- atrophic rhinitis;
- dry rhinitis;
- prostatic hyperplasia;
- surgical interventions on the meninges (in the anamnesis);
- simultaneous use with MAO inhibitors and tricyclic antidepressants;
- the period of breastfeeding;
- for a concentration of 0.05 mg + 5 mg / dose - children under 2 years of age;
- for a concentration of 0.1 mg + 5 mg / dose - children under 6 years of age.
Diabetes mellitus, pheochromocytoma, diseases of the cardiovascular system (including coronary artery disease), hypersensitivity to the action of adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, tremor, increased blood pressure.
Use in pregnancy and lactation
The use of the drug during pregnancy and during breastfeeding is contraindicated.
Use in children
for a concentration of 0.05 mg + 5 mg / dose - children under 2 years of age; for a concentration of 0.1 mg + 5 mg / dose - children under 6 years of age.
Use in elderly patients
Use with caution to avoid the risk of exacerbation of chronic diseases.
Before use, it is necessary to clean the nasal passages.
The duration of use of the drug in children is established after consulting a doctor.
Influence on the ability to drive vehicles and mechanisms
When using the drug in accordance with this instruction for use, the drug does not affect the ability to drive vehicles, however, when adverse events occur, these activities should be refrained from performing.
Symptoms: in cases of overdose or accidental oral administration, mydriasis, nausea, vomiting, cyanosis, fever, convulsions, tachycardia, heart rhythm disturbance, vascular insufficiency, cardiac arrest, arterial hypertension, pulmonary edema, respiratory failure, hallucinations may occur. Patients may also develop symptoms of CNS depression, accompanied by drowsiness, decreased body temperature, bradycardia, shock, respiratory arrest and coma.
Treatment: the use of activated charcoal, gastric lavage, oxygen ventilation of the lungs. To reduce blood pressure, 5 mg of phentolamine is prescribed in a 0.9% solution of sodium chloride by slow intravenous administration or 100 mg of phentolamine orally. Vasoconstrictor drugs are contraindicated. If necessary, antipyretic and anticonvulsant means.
The concomitant use of MAO inhibitors and tricyclic antidepressants can lead to an increase in blood pressure due to the effects of these drugs on the cardiovascular system.
Dosage and Administration
Concentration 0.05 mg + 5 mg / dose - for children from 2 to 6 years.
Concentration 0.1 mg + 5 mg / dose - for adults and children over 6 years of age.
Remove the protective cap. The bottle is ready for use.
Before the first use or after a long break in the use of the spray, press the dosing nozzle several times until uniform spraying appears.
When applying the spray, the bottle must be kept in an upright position. To ensure accurate dosing of the drug when pressing on the dosing nozzle, it is necessary to lower it down to a stop.
During injection, you need to easily inhale with your nose. One injection into each nasal passage 3-4 times / day. The duration of therapy is 5-7 days. Do not apply for more than 7 days. The duration of use of the drug in children is established after consulting a doctor.
Repeated use is possible only after a break of several days.
If after 5 days of treatment there is no improvement or the symptoms worsen, or new symptoms appear, it is necessary to consult a doctor.
The drug should be used only according to the indications, the method of use and in those doses that are indicated in the instructions.
The adverse events presented below are listed depending on the anatomical and physiological classification and frequency of occurrence. The frequency of occurrence is determined as follows: very often (≥1/10), often (≥1/100, <1/10), infrequently (≥1/1000, <1/100), rarely (≥1/10000, <1/1000), very rare (<1/10000), frequency unknown (cannot be estimated based on available data).
From the nervous system: very rarely - anxiety, insomnia, headache, fatigue (drowsiness), hallucinations (mainly in children).
From the cardiovascular system: rarely - a feeling of palpitations, tachycardia, increased blood pressure; very rarely - arrhythmia.
From the respiratory system: very rarely - swelling of the nasal mucosa, hypersecretion, bleeding from the nose; the frequency is not known - burning and dryness of the nasal mucosa, sneezing.
From the musculoskeletal system: very rarely - convulsions (especially in children).
From the immune system: very rarely - allergic reactions (angioedema, skin rash, itching).
If any of these side effects are aggravated, or any other side effects are noted, you should inform your doctor.
The drug should be stored out of the reach of children when temperature not higher than 25 ° C.
Shelf life - 3 years. Do not use after the expiration date.
Conditions of release from pharmacies
- Dosage form
- Nasal spray
- dexpanthenol + xylometazoline
- INN Russian
- Russian title