Afobazole 10mg tablets 60
Women's clothing size
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1 tablet contains morpholine ethylthioethoxybenzimidazole dihydrochloride 10 mg;
excipients: potato starch, microcrystalline cellulose, lactose, povidone, magnesium stearate.
Afobazole is a derivative of 2-mercaptobenzimidazole, a selective anxiolytic that does not belong to the class of benzodiazepine receptor agonists. Prevents the development of membrane-dependent changes in the GABA receptor. The drug has an anxiolytic effect with an activating component that is not accompanied by hypnosedative effects (the sedative effect is detected in doses 40-50 times higher than ED50 for anxiolytic action). The drug has no muscle relaxant properties, a negative effect on memory and attention. When using the drug, drug dependence is not formed and does not withdrawal syndrome develops. The effect of the drug is realized mainly in the form of a combination of anxiolytic (anti-anxiety) and easily stimulating (activating) effects. Reduction or elimination of anxiety (anxiety, bad premonitions, fears, irritability), tension (timidity, tearfulness, feeling anxious, inability to relax, insomnia, fear), and, consequently, somatic (muscular, sensory, cardiovascular, respiratory, gastrointestinal symptoms), vegetative (dry mouth, sweating, dizziness), cognitive (difficulty concentrating, weakened memory) disorders is observed for 5-7 days treatment with Afobazole.
Indications for use
Anxiety in adults:
- generalized anxiety disorders, neurasthenia, adaptation disorders;
- in patients with various somatic (bronchial asthma, irritable bowel syndrome, SLE, coronary artery disease, arterial hypertension, arrhythmias), dermatological, oncological and other diseases;
- sleep disorders associated with anxiety;
- neurocirculatory dystonia;
- premenstrual tension syndrome;
- alcohol withdrawal syndrome;
- to alleviate the withdrawal syndrome when quitting smoking.
- lactation (breastfeeding);
- age up to 18 years;
- hypersensitivity to the components of Afobazole.
Dosage and Administration
Afobazole is prescribed orally, after eating. A single dose is 10 mg; daily dose - 30 mg, divided into 3 doses during the day. The duration of the course of use of the drug is 2-4 weeks. If necessary, the daily dose of the drug can be increased to 60 mg, and the duration of treatment to 3 Months.
Allergic reactions are possible.
Rarely - a headache, which usually goes away on its own and does not require discontinuation of the drug.
The drug should be stored out of the reach of children, a dry, protected from light place at a temperature not exceeding 25 ° C.
- Dosage form
- 75 mcg
- Number of tablets
- INN Russian
- Russian title