Micrazim (Pancreatin) 10000 IU capsules 20

$24.50
Size chart
Women's clothing size
SizeXSSML
Euro 32/34 36 38 40
USA 0/2 4 6 8
Bust(in) 31-32 33 34 36
Bust(cm) 80.5-82.5 84.5 87 92
Waist(in) 24-25 26 27 29
Waist(cm) 62.5-64.5 66.5 69 74
Hips(in) 34-35 36 37 39
Hips(cm) 87.5-89.5 91.5 94 99
How To Measure Your Bust

With your arms relaxed at your sides, measure around the fullest part of your chest.

How To Measure Your Waist

Measure around the narrowest part of your natural waist, generally around the belly button. To ensure a comfortable fit, keep one finger between the measuring tape and your body.

Volume discounts

Quantity Unit discount You Save
2 28% $13.72
3 33% $24.26
4 40% $39.20
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Description
Country

Russia

INN

Pancreatin

Dosage

10000 IU

Composition

Active substance: 10000 units of Pancreatin in the form of enteric pellets (microgranules).

Excipients: pellet shell (microgranule): eudragite E-100 (methyl methacrylate, dimethylaminoethyl methacrylate and butyl methacrylate copolymer), triethyl citrate, talc, simethicone emulsion;

Composition of the capsule shell: gelatin, water, sodium lauryl sulfate, methyl parahydroxybenzoate (methylparaben, nipagin), propyl parahydroxybenzoate (propylparaben); dyes: punch dye (ponso 4R), quinoline yellow dye, patented blue dye, titanium dioxide.

Pharmacological properties

MICRASIM is an enzyme preparation from the pancreas of animals, which includes protease, lipase and amylase, which provide digestion of proteins, fats and carbohydrates of food.

After taking the drug gelatin the capsule under the action of gastric juice dissolves in the stomach and pancreatin microgranules, resistant to the acidic environment of the stomach, together with the gastric contents, enter the 12th duodenum, and then into the small intestine, where digestive enzymes are released and enzymatic digestion of food is ensured. Pancreatin in the form of microgranules provides a faster mixing of digestive enzymes with intestinal contents and their even distribution in it, which provides a higher digesting activity. The enzymatic activity of pancreatin is manifested as much as possible 30-40 minutes after oral administration. After interacting with substrates, protease, lipase and amylase in the lower intestines lose their activity and, together with intestinal contents, are excreted from the body. Micrasim is not absorbed in the gastrointestinal tract and acts locally.

Indications for use

For replacement therapy for enzyme deficiency of the pancreas, associated with: hereditary diseases - cystic fibrosis (pancreatic fibrosis), chronic pancreatitis; pancreatic tumors; surgical interventions on the pancreas. Replacement therapy for pancreatic enzyme deficiency cannot replace the treatment of the underlying disease.

Symptomatic therapy in complex treatment for the correction of digestive disorders that occur in other diseases or pathological conditions of the gastrointestinal tract: conditions after resection of the stomach, gallbladder, part of the intestine; diseases and conditions accompanied by a violation of the process of biliary excretion (liver disease, cholecystitis, gallstones, chronic diseases of the biliary tract, compression of the biliary tract by neoplasms, cystic growths, etc.);
diseases of the small intestine and duodenum, large intestine, accompanied by a violation of the advancement of the intestinal Content.

To improve the process of digestion of food in adults and children with normal gastrointestinal function in the case of:
errors in the diet (eating fatty and rough foods, overeating, irregular nutrition); with violations of masticatory function, a sedentary lifestyle, prolonged immobilization.
For use in complex preparation for X-ray examination and ultrasound of the abdominal organs.

Contraindications

Acute pancreatitis, exacerbation of chronic pancreatitis.
Hypersensitivity to the components of the drug.

Dosage and Administration

Doses of Micrazim are selected individually depending on the severity of the disease and the composition of the diet. If a single dose of the drug is more than 1 capsule, you should take half of the total number of capsules immediately before meals, and the other half - during meals, washed down with a non-alkaline liquid (water, fruit juices). If a single dose is 1 capsule, it should be take with meals. With difficulty swallowing and for children, the capsule can be opened and microgranules can be added to food that does not require chewing (for example, applesauce, yogurt). Grinding or chewing microgranules, as well as adding them to food with a pH above 5.5 leads to the destruction of their shell, which protects against the action of gastric juice. The prepared mixture must be used immediately. During enzyme therapy, it is recommended to consume a sufficient amount of fluid, fluid deficiency can cause constipation.

Cystic fibrosis. The initial estimated dose for children of the first year of life and under 4 years of age is 1000 IU lipase per kilogram of body weight at each feeding, for children older than 4 years - 500 IU lipase per kilogram at each meal. The dose should be selected individually, depending on the severity of the disease, the severity of steatorrhea and nutritional status. The maintenance dose for most patients should not exceed 10,000 IU lipase per kilogram of body weight in day.

Other types of exocrine pancreatic insufficiency.
With replacement therapy in patients with chronic pancreatitis, the doses of enzymes depend on the degree of exocrine insufficiency, as well as the individual eating habits of the patient. With steatorrhea (more than 15 g of fat in the feces per day), as well as in the presence of diarrhea and weight loss, when the diet does not give a significant effect, 25,000 units of lipase are prescribed at each meal. If necessary and good tolerability, the dose is increased to 30,000 - 35,000 units of lipase at a time. A further increase in the dose, in most cases, does not improve the results of treatment and requires a revision of the diagnosis, a decrease in the fat content in the diet and / or additional prescription of drugs - proton pump inhibitors. With an unsharply pronounced steatorrhea, not accompanied by diarrhea and weight loss, from 10,000 to 25,000 units are prescribed for admission; Allowable dose for children: up to 1.5 years - 50000 EDv day; for children over 1,5 years the daily dose of the drug should not exceed -100,000 units.

Side effects

It's possible
Allergic reactions.
Rarely
When used in high doses - diarrhea, nausea, constipation, a feeling of discomfort in the epigastric region.
With prolonged use in high doses
Perhaps the development of hyperuricosuria, hyperuricemia.
With cystic fibrosis, in case of exceeding the required dose of pancreatin, the development of strictures (fibrous colonopathy) in the ileocecal part of the ascending part of the colon is possible.

Storage conditions

Store in a dry, dark place at a temperature not exceeding 25 ° C.
Keep out of reach of children.

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Product Details

Data sheet

Brand
Avva rus
service_future
otc_05
Dosage form
Capsules
Dosage
10000 IU
INN
Pancreatin
Number of tablets
20
INN Russian
Панкреатин
Russian title
Микразим
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